| 2005-04-26 | Cornell Glen | FC Dallas | FC Dallas | Glen was traded from FC Dallas to the Columbus Crew in exchange for the Crew's second-round pick in the 2006 MLS SuperDraft and a 2005 Youth International slot. The Crew also waived forward Dante Washington in the process of completing this deal. |
| 2005-04-26 | Dante Washington | Columbus Crew | Columbus Crew | Washington was waived by the Crew as part of the deal to bring Cornell Glen to Columbus. |
| 2011-04-26 | Santiago Prim | | | Prim joined the Columbus Crew during the early stages of the 2011 season, from Argentine club San Lorenzo. |
| 2012-04-26 | Jairo Arrieta | CD Saprissa | CD Saprissa | Arrieta signed a contract with the Crew in April 2012, but because of restrictions in the transfer window did not play his first game until July of that year. |